On June 2, 1895, U.S. Patent No. 541923 issued to Thomas A. Edison on the phonograph.
On May 26, 1868, U.S. Patent No. 78,317 issued to Alfred Nobel in an Improved Explosive Compound (dynamite).
On May 25, 1948, U.S. Patent No. 2,442,141 issued to Andrew J. Moyer on a Method of Production of Penicillin.