On October 1, 2002, Carl E. Hanson received U.S. Patent No. 6,457,474 on a Method of Treating Chest Pain:

Hanson’s medical breakthrough, apparently based upon a clinical study of one, is to administer lime juice instead of nitroglycerin to treat chest pain:

The patent expired July 31, 2017, removing the threat of contributory infringement or inducement of infringement of bartenders everywhere, who no longer have to make sure their patrons are not suffering from chest pains before serving that gimlet, Moscow mule, or Margarita.