On March 11, 1791, Samuel Mullikin of Philadelphia, became the United States’ first multipatent inventor. In fact, Samuel obtained four patents on March 11, 1791: a MACHINE FOR RAISING A NAP ON CLOTHS; a MACHINE FOR THRASHING GRAIN AND CORN; a BREAKING AND SWINGLING OF HEMP, ETC; and MACHINE FOR CUTTING AND POLISHING STONE AND MARBLE. Samuel received a fifth patent on January 15, 1795, on HEMP AND FLAX BREAKING; and a sixth patent on February 20, 1797, on SCOURING OR SKINNING RICE. Unfortunately, records of these patents were destroyed in the Patent Office fire on December 15, 1836.
While Samuels was the first multipatent inventor, there are hundreds of inventors who reached the same achievement between 1790 and 1828, and many, many more subsequently. Shunpei Yamazaki of Japan is current the most prolific inventor, listed as the inventor in 6517 patents.